Diagnose FIP

Published on 4 Feb. 2008 by alex

The diagnosis of peritonitis Feline infections is and remains a challenge - especially the unequivocal evidence of the disease is basically only at a terminal already infected animal or by an autopsy is possible.

Unfortunately, the difficulty of the clear diagnosis of FIP meant that it has become common practice, cats with a Coronoar anti-virus twill titre (FCoV titre) of over 1:400 / package as "FIP cats" stamp. It allows neither the Vorhandesein a titre nor the height of the titre a prediction about the outbreak of FIP (vetmedlabor [PDF]). Even if Laboklin when comparing the antibody titers clinically suspected with a group of healthy cats come to the conclusion that the FIP group suspected higher antibody titers more frequent than in the healthy group, are themselves in the group with high antibody Titer (from 1:800) still healthy cats 7% (see table below Source: Laboklin)

Titer <1: 400 Titre 1: 400 Titre 1: 800
healthy (%) 54.3 38.3 7.4
FIP suspect (%) 18.3 37.6 44.1

To diagnose a disease FIP is the determination of FCoV-titre and can not adequately insulated itself misleading. Therefore, at a screening FIP always more diagnostic laboratory findings with used. These are:

  • FIP AK-proof: The presence of coronavirus antibodies correlates well with a little actual disease, such as the height of the titre. Total Protein: Typically for a sick cat to FIP is an increase in the serum protein concentration, reflecting an increase of globulins is due (see above).
  • Eiweißelektrophorese: The serum protein is Electrophoretically groups in the albumin, α1, α2-, β-and γ-globulin separated. Sera from infected cats to FIP show significant reduction of albumin Group as well as an increase in γ-globulin Group. However, the α-and β-globulin groups be increased.
  • Albumin / globulin quotient: The significant majority of the diseased cats to FIP shows an albumin / globulin ratio of below 0.8.
  • ALT and bilirubin: An FIP diseased cats often have elevated ALT and bilirubin values.
  • Large blood: The first blood usually inconspicuous shows with increasing duration of a progressive disease anemia, a core Neutrophilie with left shift and a lymphopenia. (Source: (vetmedlabor [PDF]).

The typical FIP screening of a sick cat to FIP is as follows (Source: (vetmedlabor [PDF]).:

Electrophoresis Score Reference Range Unity
Total protein 10.5 (5,7-9,4) g / dl
A / G 0.35 (> 0.76)
Albumin 25.8 (45,0-60,0) %
α1 globulin 7.0 (4,0-14,0) %
α2 globulin 9.1 (7,0-12,0) %
β globulin 16.3 (16,0-31,0) %
γ globulin 41.8 (10,0-28,0) %
Hematopoietic Score Reference Range Unity
Leukocytes 14.9 (6-11) G / l
Erythrocytes 4.08 (5-10) T / l
Hemoglobin 4.82 (9-15) g / dl
Hämatrokrit 16.0 (30-44) %
MCV 40.0 (40-55) fl
HBE 12.0 (13-17) pg
MCHC 30.0 (31-35) g / dl
Platelets 185.0 (180-550) G / l
Differential blood Score
Ref.bereich
Unity
Basophils granulocytes 0 (0-1) %
Eosinophilic granulocytes 0 (0-4) %
Stabkernige granulocytes 11 (0-4) %
Segmentkernige granulocytes 79 (60-75) %
Lymphocytes 6 (25-30) %
Monocytes 4 (0-5) %
Atypical cells 0 (negative)
Anisozyten + (negative)
Polychromasie 0 (negative)
Score Ref.bereich Unity
ALT 122.0 (until 70) U / l
Bilirubin 2.9 (up 0.3) mg / dl
Coronarvirus-antibody 1:800 (negative)

The picture "Cat in Veterinary Procedure" was written by Jeffrey Beall on Flickr under a Creative Commons license available. The cat in the picture will not, as yet else in the U.S. customary, the claws withdrawn. Instead, she gets so-called "Softcabs", an animal-friendly (re) alternative.

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